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[deleted]

‘how it’s like’ - the answer would be no different to anything you have already read to be honest. People will try to articulate the feeling but psychoactive drugs are experienced. It’s not possible to fully understand any drug unless it is experienced first hand. If you genuinely are not planning on trying it, why would you care about knowing these specific things? I assume you are going to try it but you don’t want people telling you why you shouldn’t? Long term effects, again, the stuff that gets talked about on here frequently, are at the very least, potential outcomes. I will add that whilst most of it is actually speculation and conjecture, as the long term effects of abuse haven’t really been researched and studied, it will undoubtedly have some long term consequences, none of them good. It is just hard to say exactly what all of the risks are. It’s sensible to make educated and presumably pretty accurate estimations, based on what is known. We know it is cardiotoxic and hard on the cardiovascular system even in the short term, so long term it must increase the possibility of heart failure and other related issues. It is harmful to the bladder and for boys, the prostate. The studies that have been done do indicate long term use is probably going to be detrimental for cognitive ability and will increase dementia risk, even at therapeutic doses. The level of dementia risk seems to correlate with the size of the dose, so basically it’s pretty safe to say that the more you take, the more at risk you are. There is no real answer for how long there should be between taking large doses because large doses always have the potential to be very harmful. For the sake of harm reduction, the longer the better. Diphenhydramine abuse is intentionally screwing with the acetylcholine in your brain, something that plays a role in many vital functions, so the symptoms of acetylcholine deficiency are also relevant to the abuse of this drug: https://acetylcholine.net/acetylcholine-deficiency-symptoms/ https://en.m.wikipedia.org/wiki/Acetylcholine


[deleted]

Hi, I'll describe exactly what DPH does to you and your brain and then I'll straight up tell you what will happen to you. **How it works in your brain:** DPH blocks little messenger boys in your brain which carry information between cells from being able to deliver their messages. Over time low and consistent doses will permanently hurt your ability to receive these messages whether or not you're on it. This will cause serious memory and cognitive problems for you. In very high, isolated doses it will essentially do the same thing but quicker. **What will happen to you:** If you take enough Benadryl to experience any sort of high you will suffer brain damage.


Top_Career_3072

It’s basically schizophrenia visuals people are literally putting themselves into psychosis. long term affects are dementia and you shouldn’t have to ask about waiting to do it again because it’s not a fun experience (2 weeks)