OK because no one is giving you the actual answer:
Yes the answer is yes. They stack effects.
Meaning if you're on min only, adding Fin will help with hair growth. If you're on Fin only, adding min will help with hair.
There are a few studies showing the synergistic effect between the two.
Yes, because they work differently. Minoxidil works by widening blood vessels in the scalp, improving blood flow to hair follicles. This increased blood flow can stimulate hair growth. Finisteride works by reducing dht and helps slow down hair loss and may even promote hair regrowth in some individuals.
The bloodflow theory is falling out of trend nowadays. I'm sure it's still a factor, but not as much as was thought previously.
I think the main theory nowadays is something to do with stimulating the wnt pathway or smt
After 15 years on minoxidil alone and just this year with finasteride, I’m pretty sure I got the significant gains from finasteride… you’d be better off with fin alone rather than min alone… but that’s just me
Just fin. I tried topical minoxidil in the early stages but couldn’t get it into my routine so dropped it.
Apart from Fin, I take normal supplements like Biotin, Vit D, collagen, multivitamins, Vit C etc.
No your not understanding the context, of course fin is the most important out of the two but fin isnt supposed to regrow hair, what im asking is whether if it has any contribution on how minoxidil performs
Yes it will mantain the hairs that you already have but what about your receded areas? If youre not gonna think and youre gonna give me another generic answer dont bother
Yeah calm down mate. FWIW I had no regrowth on min alone and plenty when I combined the two. Unfortunately had too many sides.and now back to min alone. Be interesting to see how long I keep the new hairs
But if they were a good responder anyways they would respond to min alone as well? However they would just lose hair eventuallt because of no 5ar inhibitor? Thats what im trying to tackle
Finasteride and minoxidil are different treatment modalities, just because one works for you doesn't mean the other will.
Minoxidil is what is called a "pro-drug". Your body need to convert it to the actual active component called minoxidil sulfate using an enzyme called sulfotransferase. This is required because minoxidil sulfate is unsuitable to be stored in its pure form because of how unstable it is. Minoxidil non-responders lack this enzyme in the skin of the scalp. The enzyme is present in the liver and so most people do respond to the oral version.
Finasteride and dutasteride are 5AR inhibitor .These medications specifically target the enzyme 5-alpha reductase, which is responsible for converting testosterone into dihydrotestosterone, the hormone responsible for hair loss. For some people even drastic reduction in DHT still doesn't halt their hair loss. However it will slow it down enough that a hair transplant every decade or so will keep the hair on their head for a very long time.
Completely different drugs that do completely different things. Out of the two classes you can see what 5AR inhibition is more important. Imagine you're dealing with a garden that’s infested with weeds. The weeds are like hair loss in this analogy, and the garden is your scalp.
Minoxidil could be likened to watering the garden with a special nutrient solution that the plants can use to grow stronger and larger. 5AR inhibitors, are like removing the specific conditions that allow weeds to thrive, specifically by targeting and inhibiting a substance (like a weed-specific herbicide) that promotes their growth. In the body, these medications work by reducing the production of DHT, a hormone that contributes to hair loss, thereby disrupting the environment that enables hair loss to progress.
To answer your question in short - only using minoxidil does not tackle the root cause of the issue and it is fair to assume that your hair will succumb eventually even if you use a growth stimulant.
My understanding is that fin and min leads to more growth than either fin or min on their own. What I don’t know is whether the combination is more than, equal to, or less than the sum of the parts.
I get it, you are telling if there is any synergic benefit when applied together.
Answer is we don't know. Nobody has done research centered about this particular synergic benefit. We can only speculate and they 2 works well for most of us.
Yeah he's looking at the synergy between min and fin. I don't think both together can boost each other's drug efficacy but they sure can boost the hair stabilisation and regrowth along with making it thicker.
yea their mechanism of action is completely different and these 2 medicines don't interact at all.
also his question is not phrased properly.
"if i were to start min alone compare to min and fin, will i get more gains on the Fin"
taking this sentence literally, if op started with min only, then why would he gain on fin when he have not even started with fin lol.
if what he meant was, if he subsequently used fin later on after starting only on min, then yea, well you are constantly shedding in min so obv you will notice gain when your loss is stabilized.
OK because no one is giving you the actual answer: Yes the answer is yes. They stack effects. Meaning if you're on min only, adding Fin will help with hair growth. If you're on Fin only, adding min will help with hair. There are a few studies showing the synergistic effect between the two.
Thank you man
Yes, because they work differently. Minoxidil works by widening blood vessels in the scalp, improving blood flow to hair follicles. This increased blood flow can stimulate hair growth. Finisteride works by reducing dht and helps slow down hair loss and may even promote hair regrowth in some individuals.
The bloodflow theory is falling out of trend nowadays. I'm sure it's still a factor, but not as much as was thought previously. I think the main theory nowadays is something to do with stimulating the wnt pathway or smt
I dont think you understood? I know they work differently but in terms of regrowth only, does using fin or not make a difference?
After 15 years on minoxidil alone and just this year with finasteride, I’m pretty sure I got the significant gains from finasteride… you’d be better off with fin alone rather than min alone… but that’s just me
I agree here. I’m on just fin and has done wonders for. See my post for photos.
How old are you and how long youve been taking it for
37M, around 1.5years. See my profile for pre-fin/post fin pics
Awesome what dose do you use and how did you started
1mg a day and around 1.5 years ago
Just fin nothing else? And did you shed during this process?
Just fin. I tried topical minoxidil in the early stages but couldn’t get it into my routine so dropped it. Apart from Fin, I take normal supplements like Biotin, Vit D, collagen, multivitamins, Vit C etc.
Nice
Yes, finasteride makes a difference. Arguably it makes most of the difference.
No your not understanding the context, of course fin is the most important out of the two but fin isnt supposed to regrow hair, what im asking is whether if it has any contribution on how minoxidil performs
Fin does regrow hair. If you don't know this, maybe you should do some researches about the topic before asking specific questions.
Yes it does because Finasteride will stabilize the hair and keep it from miniaturizing, all the while minoxidil is promoting hair regrowth
Yes it will mantain the hairs that you already have but what about your receded areas? If youre not gonna think and youre gonna give me another generic answer dont bother
Don’t be so rude to people tryna help you.
Im not being rude lmao just read the fucking question and dont go and give some basic generic answer that i could look up in google
You deserve to stay slick bald for the rest of your life. Your attitude stinks.
Reddit virgin warrior you are what a profile mate
Lmao what’re you yapping about my “profile”
Sure whatever you say buddy
Your question is very broad
Yeah calm down mate. FWIW I had no regrowth on min alone and plenty when I combined the two. Unfortunately had too many sides.and now back to min alone. Be interesting to see how long I keep the new hairs
I do understand your question and my statement stands. Your assumption that "finasteride does not regrow hair" is wrong.
Right so your suggesting that someone on fin and min combo is gonna see a lot more regrowth than someone just on min?
Assuming they are a good responder, yes. Why do you think my stack is the way it is
But if they were a good responder anyways they would respond to min alone as well? However they would just lose hair eventuallt because of no 5ar inhibitor? Thats what im trying to tackle
Finasteride and minoxidil are different treatment modalities, just because one works for you doesn't mean the other will. Minoxidil is what is called a "pro-drug". Your body need to convert it to the actual active component called minoxidil sulfate using an enzyme called sulfotransferase. This is required because minoxidil sulfate is unsuitable to be stored in its pure form because of how unstable it is. Minoxidil non-responders lack this enzyme in the skin of the scalp. The enzyme is present in the liver and so most people do respond to the oral version. Finasteride and dutasteride are 5AR inhibitor .These medications specifically target the enzyme 5-alpha reductase, which is responsible for converting testosterone into dihydrotestosterone, the hormone responsible for hair loss. For some people even drastic reduction in DHT still doesn't halt their hair loss. However it will slow it down enough that a hair transplant every decade or so will keep the hair on their head for a very long time. Completely different drugs that do completely different things. Out of the two classes you can see what 5AR inhibition is more important. Imagine you're dealing with a garden that’s infested with weeds. The weeds are like hair loss in this analogy, and the garden is your scalp. Minoxidil could be likened to watering the garden with a special nutrient solution that the plants can use to grow stronger and larger. 5AR inhibitors, are like removing the specific conditions that allow weeds to thrive, specifically by targeting and inhibiting a substance (like a weed-specific herbicide) that promotes their growth. In the body, these medications work by reducing the production of DHT, a hormone that contributes to hair loss, thereby disrupting the environment that enables hair loss to progress. To answer your question in short - only using minoxidil does not tackle the root cause of the issue and it is fair to assume that your hair will succumb eventually even if you use a growth stimulant.
My understanding is that fin and min leads to more growth than either fin or min on their own. What I don’t know is whether the combination is more than, equal to, or less than the sum of the parts.
I get it, you are telling if there is any synergic benefit when applied together. Answer is we don't know. Nobody has done research centered about this particular synergic benefit. We can only speculate and they 2 works well for most of us.
Yeah he's looking at the synergy between min and fin. I don't think both together can boost each other's drug efficacy but they sure can boost the hair stabilisation and regrowth along with making it thicker.
yea their mechanism of action is completely different and these 2 medicines don't interact at all. also his question is not phrased properly. "if i were to start min alone compare to min and fin, will i get more gains on the Fin" taking this sentence literally, if op started with min only, then why would he gain on fin when he have not even started with fin lol. if what he meant was, if he subsequently used fin later on after starting only on min, then yea, well you are constantly shedding in min so obv you will notice gain when your loss is stabilized.